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Figure 9 | BMC Microbiology

Figure 9

From: Characterization of the mrgRS locus of the opportunistic pathogen Burkholderia pseudomallei: temperature regulates the expression of a two-component signal transduction system

Figure 9

Alignment of lipases of B. pseudomallei isolates 112 and 204. Boxes enclose the "lid" motif (residues 112–127) and serine active site (residues 187–191). Asterisks mark the catalytic triad of serine, aspartic acid and histidine. +: conservative amino acid substitutions. Non-conservative amino acid substitutions are underlined. The 6 substitutions that are marked were also present in many of the B. pseudomallei genome sequences of 10 isolates that are available in GenBank: S47N: 10 isolates; I157V: 10 isolates; G180E: 5 isolates; V229A: 9 isolates; N340D: 4 isolates; E346Q: 3 isolates. Other substitutions were also found occasionally: S252F: 1 isolate; D341A: 1 isolate; V249L: 1 isolate.

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