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Figure 5 | BMC Microbiology

Figure 5

From: The Bacillus anthracis cholesterol-dependent cytolysin, Anthrolysin O, kills human neutrophils, monocytes and macrophages

Figure 5

Hemolytic activity of BHI growth supernatants of B. anthracis strains 7702, the parent ALO+ strain, and UT231(pUTE544), the ALO knockout strain complemented in trans with a plasmid bearing the alo gene. UT231 (pUTE544) produces about 1,000-fold more ALO. Hemolytic activity is reduced upon the addition of 1 μg/ml cholesterol. Results are representative of at least three independent experiments done in duplicate.

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