Table 1 This table presents the genes that were consistently and statistically up regulated in the hypothetically more pathogenic lineage I strains.
From: Microarray based comparison of two Escherichia coli O157:H7 lineages
Name | average mean log ratio (635/532) | average fold increase | One Sample t-Test (p) | definition | accession |
|---|---|---|---|---|---|
hslJ | -2.04 | 4.10 | 0.017036 | heat shock protein hslJ | NP_287767.1 |
cspG | -1.97 | 3.91 | 0.018217 | homolog of Salmonella cold shock protein | NP_286926.1 |
ibpB | -1.82 | 3.54 | 0.037563 | heat shock protein | NP_290325.1 |
ibpA | -1.59 | 3.02 | 0.031977 | heat shock protein | NP_290324.1 |
Fimb 10 | -1.58 | 2.98 | 0.011803 | putative fimbrial protein | NP_290361.1 |
trxC | -1.39 | 2.63 | 0.018467 | putative thioredoxin-like protein | NP_289141.1 |
feoB | -1.31 | 2.47 | 0.004959 | ferrous iron transport protein B | NP_289949.1 |
ureD | -1.28 | 2.43 | 0.038695 | putative urease accessory protein D | NP_287085.1 |
chap3 | -1.26 | 2.39 | 0.030462 | possible chaperone | NP_288034.1 |
ydeA | -1.23 | 2.35 | 0.026584 | putative resistance/regulatory protein | NP_287624.1 |
ureD_2 | -1.23 | 2.34 | 0.050155 | putative urease accessory protein D | NP_287085.1 |
secret3 | -1.09 | 2.13 | 0.024694 | putative secreted protein | NP_288394.1 |
fliC | -1.06 | 2.08 | 0.018058 | flagellar biosynthesis; flagellin, filament structural protein | NP_288384.1 |
stx2A | -1.00 | 2.01 | 0.021712 | shiga-like toxin II A subunit encoded by bacteriophage BP-933W | NP_286976.1 |
terW | -0.95 | 1.93 | 0.044205 | unknown associated with putative tellurite resistance | NP_286699.1 |
rfaH | -0.93 | 1.90 | 0.007198 | transcriptional activator affecting biosynthesis of lipopolysaccharide core, F pilin, and haemolysin | NP_290472.1 |
phoB | -0.87 | 1.82 | 0.006296 | positive response regulator for pho regulon, sensor is PhoR (or CreC) | NP_286137.1 |
ureA_2 | -0.81 | 1.75 | 0.050244 | putative urease structural subunit A (gamma) | NP_287086.1 |
helicase1 | -0.71 | 1.64 | 0.01929 | putative ATP-dependent helicase | NP_288767.1 |
yegW | -0.71 | 1.63 | 0.015902 | putative transcriptional regulator | NP_288603.1 |
ureB_2 | -0.70 | 1.62 | 0.038644 | putative urease structural subunit B (beta) | NP_287087.1 |
typeIIIap7 | -0.66 | 1.58 | 0.033765 | type III secretion apparatus protein | NP_289424.1 |
ycjZ | -0.61 | 1.53 | 0.038253 | putative transcriptional regulator LYSR-type | NP_287857.1 |
ykgA | -0.60 | 1.51 | 0.000965 | putative AraC-like transcriptional regulator | NP_286025.1 |
sbmA | -0.59 | 1.50 | 0.050279 | sensitivity to microcin B17, possibly envelop protein | NP_286115.1 |
YjhS | -0.57 | 1.49 | 0.03404 | orf, hypothetical protein | NP_290925.1 |
ybbK | -0.53 | 1.45 | 0.037791 | putative protease | NP_286238.1 |
virulense3 | -0.50 | 1.42 | 0.038974 | putative virulence gene | NP_290837.1 |
pldA | -0.49 | 1.41 | 0.031981 | outer membrane phospholipase A | NP_290453.1 |
yejH | -0.48 | 1.40 | 0.008115 | putative ATP-dependent helicase | NP_288767.1 |
transreg | -0.34 | 1.27 | 0.033811 | putative membrane spanning transport protein | NP_286232.1 |
hydH | -0.27 | 1.21 | 0.00039 | sensor kinase for HydG, hydrogenase 3 activity | NP_290635.1 |