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Table 1 Families of Transcriptional regulatory proteins in bacteria and archaea.

From: ExtraTrain: a database of Extragenic regions and Transcriptional information in prokaryotic organisms

Family

InterPro entry

ExtraTrain entries

Action

Structural motif

DBD position

AraC/XylS

IPR000005 HTHAraC

2485

Activator

HTH

C-terminal

ArsR

IPR001845 HTH_ArsR

982

Repressor

HTH

Central

AsnC

IPR000485 HTH_AsnC_lrp

803

Dual

HTH

N-terminal

Cold shock domain

IPR002059 Cold_shock

607

Activator

RNA- binding like

Variable

CRP-FNR

IPR001808 HTH_Crp

414

Activator/Dual

HTH

C-terminal

DeoR

IPR001034 HTH_DeoR

680

Repressor

HTH

N-terminal

GntR

IPR000524 HTH_GntR

1989

Repressor

HTH

N-terminal

IclR

IPR005471 HTH_IclR

538

Repressor

HTH

N-terminal

LacI

IPR000843 HTH_LacI

1079

Repressor

HTH

N-terminal

LuxR

IPR000792 HTH_LuxR

2117

Activator

HTH

C-terminal

LysR

IPR000847 HTH_LysR

3864

Dual

HTH

N-terminal

MarR

IPR000835 HTH_MarR

1316

Dual

HTH

Central

MerR

IPR000551 HTH_MerR

1112

Repressor

HTH

N-terminal

NtrC/Fis

IPR002197 HTH_Fis

3089

Activator

HTH

C-terminal

OmpR

IPR001867 Trans_reg_C

2253

Activator

winged helix

C-terminal

TetR

IPR001647 HTH_TetR

2718

Repressor

HTH

N-terminal

  1. This table contains information about the 16 families of transcription factors included in ExtraTrain database. The first column contains the name of each family. The second column contains the identifier of the InterPro entry that defines each family. The third column contains the number of members of each family included in the database. The fourth column indicates if the members of this family usually are activators, repressors or have a dual action. The fifth column indicates the protein structural motif involved in the DNA interaction. The last column indicates the N or C-terminal position of the DNA-binding domain in the sequence of the regulatory protein.