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Table 2 Km of PDEs

From: Cyclic nucleotide specific phosphodiesterases of Leishmania major

PDE cAMP (μM) cGMP (μM) Refs
LmPDEB1 0.99 --- *)
LmPDEB2 6.98 --- *)
TbrPDEB1/TbPDE2C 7.97 --- [20]
TbrPDEB2/TbPDE2B 2.4 --- [21]
HsPDE1A1 112.7 5.0 [38]
HsPDE1B1 24.3 2.7 [38]
HcPDE1C2 1.2 1.1 [38]
HsPDE2 30 – 50 15 – 30 [38]
HsPDE3 0.1–0.8 0.1– 0.8 [38]
HsPDE4 1 – 3 --- [38]
HsPDE5 > 300 1 – 5 [38]
HsPDE6 910 14 [39]
HsPDE7 0.2 – 1 --- [38]
HsPDE8 0.06 – 0.15 124 [38]
HsPDE9 320 0.007–0.17 [38]
HsPDE10 0.05 3 [38]
HsPDE11 0.5 1 [38]
  1. *) this work