Cereulide synthetase gene cluster from emetic Bacillus cereus: Structure and location on a mega virulence plasmid related to Bacillus anthracis toxin plasmid pXO1

Table 2 Deduced function of encoded proteins in the ces operon and flanking regions

Protein^a	Length of product (aa)	Deduced function (Homology)
CDS 1	63	Hypothetical protein (pXO1 related)
CDS 2	159	CAAX amino terminal protease
CDS X14	565	Conserved protein (Clp ATPase^b) (pXO1-14 like)
Ces gene cluster		Cereulide biosynthesis
CesH	269	Hydrolase/Acyltransferase
CesP	251	Phosphopantheteinyltransferase
CesT	237	Type II Thioesterase
CesA	3391	NRPS (Cereulide synthesis)
CesB	2681	NRPS (Cereulide synthesis)
CesC	291	ABC transporter
CesD	268	ABC transporter, Permease
CDS X11	137	Hypothetical protein (pXO1-11 like)
CDS X23	642	Group II Intron (Reverse transcriptase, maturase)
CDS X10	333	Hypothetical protein (Methyltransferase^b) (pXO1-10 like)

a) CDS designation: CDSs with homolgies to pXO1 CDSs are indicated by "X" and the corresponding CDS number of pXO1; CDSs belonging to the ces gene cluster are named ces; b) Putative function as determined by Ariel et al., [54].

ISSN: 1471-2180