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Table 3 LSMean values with Standard errors of the TIMP1 gene transcripts. Depicts the LSMean values with Standard errors of the TIMP1 gene transcripts expressed by macrophages over time and measured by Real Time RT PCR as described in materials and methods.

From: Cytokine responses of bovine macrophages to diverse clinical Mycobacterium avium subspecies paratuberculosis strains

Strain Time post infection
  2 hour 16 hour 24 hour 48 hour 96 hour
B1018 6.45 ± 0.28 16.65 ± 8.57 6.2 ± 0.09 11.63 ± 1.42 45.9 ± 8.74
S7565 12.4 ± 1.88 2 ± 0.67 5.74 ± 1.9 9.26 ± 0.5 25.2 ± 0.25
Hu6 3.12 ± 0.79 0.87 ± 0.16 1.1 ± 0.34 2.3 ± 0.3 34.6 ± 5.7
M. avium 2.62 ± 0.18 3.2 ± 1.5 3.5 ± 0.07 4.2 ± 0.36 6.4 ± 1.25
PC1x 6.1 ± 0.6 3.8 ± 0.04 10.7 ± 1.52 36.4 ± 3.39 159.7 ± 1.57
PC2y 6.3 ± 0.34 24 ± 1.53 2.2 ± 0.65 52.3 ± 6.91 38.6 ± 5.1
NCz 6.2 ± 0.91 26.6 ± 3.91 49.8 ± 23.26 584.2 ± 71.4 8.1 ± 3.46
  1. x indicates positive control 1 (PC1) – cells stimulated with LPS
  2. y indicates positive control 2 (PC2) – cells stimulated with LPS in conjunction with recombinant bovine Interferon gamma
  3. z indicates negative control (NC) – unstimulated cells