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Table 1 LSMean values with Standard errors of the MMP3 gene transcripts. Depicts the LSMean values with Standard errors of the MMP3 gene transcripts expressed by macrophages over time and measured by Real Time RT PCR as described in materials and methods. Values with same superscript (a, b, c, p, q, r) indicate significant differences among the strains at that time point PI.

From: Cytokine responses of bovine macrophages to diverse clinical Mycobacterium avium subspecies paratuberculosis strains

Strain Time post infection
  2 hour 16 hour 24 hour 48 hour 96 hour
B1018 44.3 ± 4.77 574.6 ± 315a 259.4 ± 50.5p 121.6 ± 26 72.3 ± 24.3
S7565 55.6 ± 5.17 25.7 ± 6.6b 10057 ± 2104p,q,r 5451 ± 453 406 ± 17.9
Hu6 5.4 ± 0.2 25 ± 3.9c 134 ± 19.6r 319 ± 6.2 61.2 ± 10.7
M. avium 22.3 ± 2.2 6794 ± 133a,b,c 846 ± 107q 166.7 ± 22.8 149 ± 3.6
PC1x 56.6 ± 8.5 555 ± 51.6 26180 ± 4595 16742 ± 2938 1840 ± 678
PC2y 188.8 ± 39 15825 ± 2625 8164 ± 160 35563 ± 3307 554 ± 8.1
NCz 14.8 ± 7.5 43.9 ± 3.6 398 ± 29.4 2629 ± 77.3 1.7 ± 0.18
  1. x indicates positive control 1 (PC1) – cells stimulated with LPS
  2. y indicates positive control 2 (PC2) – cells stimulated with LPS in conjunction with recombinant bovine Interferon gamma
  3. z indicates negative control (NC) – unstimulated cells