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Table 3 Influence of inoculum size in cell production of Streptococcus pneumoniae INS-E611 after 12 hours of Phase 1 culture in supplemented THB

From: Optimization of culture conditions to obtain maximal growth of penicillin-resistant Streptococcus pneumoniae

Number of CFU (Phase 0)

OD600 nm (Phase 1)

Broth pH (Phase 1)

Phase 1 Production [log10 CFU/mL]

1

0.381

7.90

7.278

5

1.878

7.00

8.662

10

0.914 – 1.884

7.08 – 7.32

8.884 ± 0.047

15

1.766

6.28

9.067

Loopful

1.778

6.17

8.851