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Table 1 Serotypes and minimal inhibitory and bactericidal concentrations (MIC / MBC) of six antimicrobial agents against nine strains of Streptococcus pneumoniae

From: Optimization of culture conditions to obtain maximal growth of penicillin-resistant Streptococcus pneumoniae

Strains

Serotype

MIC / MBC [μg/mL]

MIC* [μg/mL]

  

PEN

CRO

VAN

ERY

CHL

SXT

INS-E611

6B

2.00 / 2.00

1.00 / 1.41

0.35 / 0.35

0.03

32.00

4.00

INS-E674

14

2.00 / 2.00

1.00 / 1.00

0.25 / 0.25

0.06

4.00

8.00

INS-E676

14

1.00 / 1.41

1.00 / 1.41

0.35 / 0.70

0.06

4.00

8.00

INS-E678

14

0.12 / 0.12

0.03 / 0.03

0.25 / 0.25

0.06

4.00

16.00

INS-E682

6B

0.01 / 0.01

0.01 / 0.01

0.25 / 0.25

0.06

32.00

0.50

INS-E683

9V

1.00 / 1.00

0.35 / 0.35

0.35 / 0.35

0.06

4.00

32.00

INS-E684

14

1.00 / 1.00

0.50 / 0.50

0.25 / 0.25

0.13

4.00

1.00

INS-E685

1

0.01 / 0.01

0.01 / 0.01

0.25 / 0.25

0.06

2.00

0.50

ATCC 49619

19F

0.46 / 0.46

0.06 / 0.12

0.33 / 0.44

0.06

4.00

0.25

  1. PEN = penicillin; CRO = ceftriaxone; VAN = vancomycin; CHL = chloramphenicol; ERY = erythromycin; SXT = trimethoprim-sulfamethoxazole (only first component values shown)
  2. * MIC determined by Instituto Nacional de Salud (INS), Bogotá, Colombia.
  3. Breakpoint for penicillin-susceptible strains: MIC ≤ 0.06 μg/mL.