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Table 1 dnaA alleles used in this work and some phenotypes

From: Allele specific synthetic lethality between priC and dnaAts alleles at the permissive temperature of 30°C in E. coli K-12

Allele Amino Acid Change Domain Affecteda Ability to replicate P+ plasmids at 30°Cb Ability to grow in priC303::kan at 30°C
dnaA46 A184V
H252Y
III
III
No No
dnaA508 P28L
T80I
I
I
No No
dnaA5 A184V
G426S
III
IV
Yes Yes
dnaA167 V157E III Yes Yes
dnaA204 I389N IV No Yes
dnaA602 A184V
A347V
III
linker
Yes Yes
  1. aDomains are defined according to [25, 35, 36].
  2. bData from [34]