Table 3 In vitro growth inhibition of M tuberculosis and M. marinum by aminooxy compounds. One hundred μL of a mid-logarithmic culture of M. tuberculosis or M. marinum at a concentration of 2 × 10⁵ cfu/ml was added to 100 μL of serial doubling dilutions of inhibitor in a 96-well microtitre plate. The drug plates were grown for 14 days at 37°C (M. tuberculosis) or 8 days at 30°C (M. marinum) with no agitation before checking for cell growth at A_{650 nm}. The minimum inhibitory concentration (MIC) and inhibitory concentration 50% (IC50) were calculated as described in the Methods section.

From: Branched-chain amino acid aminotransferase and methionine formation in Mycobacterium tuberculosis