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Figure 4 | BMC Microbiology

Figure 4

From: Characterization of HPV16 L1 loop domains in the formation of a type-specific, conformational epitope

Figure 4

An anti-HPV16 VLP type-specific monoclonal antibody recognizes a conformation-dependent epitope presented by loops I and II. a, Capsomere assembly was verified via SDG analysis and by TEM (data not shown). Percent capsomere assembly was determined as per SDG approach with final results as indicated. b, Quantitative ELISA testing the panel of loop swap mutants, HPV16 GST-L1 (positive control) and COPV GST-L1 (negative control) with anti-HPV16 VLP monoclonal antibody 16A.

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