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Table 2 Effect on the adhesion of wild type S. dysenteriae, S. flexneri BS176 and wild type S. sonnei of. whey. PIS (sIgA). P2H (fSC) and P3H (Lf).

From: In vitro adhesion and invasion inhibition of Shigella dysenteriae, Shigella flexneri and Shigella sonnei clinical strains by human milk proteins

 

S. dysenteriae wild type

S. flexneri BS176

S. sonnei wild type

 

Bacteria

n°/Hela cell

% inhibition

p

Bacteria

n°/Hela cell

%inhibition

p

Bacteria

n°/Hela cell

% inhibition

p

Fraction

Control

tested

  

control

tested

  

control

tested

  

Whey

28.5 ± 3.0

12.5 ± 1.5

66

0.001

19 ± 8.0

5.7 ± 0.4

59

0.03

7.2 ± 1.6

2.64 ± 0.32

63

0.002

sIgA

22.5 ± 0.2

15.0 ± 0.4

33

0.012

8.0 ± 3.0

3.5 ± 1.0

56

0.02

8.8 ± 1.6

5.28 ± 0.8

40

0.025

fSC

24.0 ± 3.0

10.5 ± 4.5

56

0.009

13.0 ± 0.4

3.8 ± 0.8

71

0.01

8.8 ± 0.24

3.52 ± 0.8

60

0.001

Lf

29.5 ± 4.0

13.0 ± 0.5

56

0.009

7.0 ± 0.6

2.0 ± 0.2

71

0.007

7.2 ± 0.96

3.52 ± 1.6

51

0.008

  1. p = statistical analyses (t-Student independent)