BMC Microbiology

Table 1 Effect on invasion of S. dysenteriae. S. flexneri and S. sonnei of whey, casein, PIS (sIgA), P2S (Lf, SC and albumin, SA), P3S (α-lactoalbumin), P2H (fSC and SA) and P3H (Lf).

From: In vitro adhesion and invasion inhibition of Shigella dysenteriae, Shigella flexneri and Shigella sonnei clinical strains by human milk proteins

	S. dysenteriae wild type				S. flexneri wild type				S. sonnei wild type
	Bacteria	n°/Hela cell	% inhibition	p	bacteria	n°/Hela cell	% inhibition	p	bacteria	n°/Hela cell	% inhibition	p
Fraction	control	Tested			control	tested			control	tested
Whey	5.2 ± 0,4	2.2 ± 0,2	58	0.001	0.68 ± 0.2	0.28 ± 0.2	74	0.007	0.49 ± 0.24	0.18 ± 0.15	62	0.008
casein	6.6 ± 1,0	6.5 ± 1,1	-	ns	0.89 ± 0.1	0.83 ± 0.2	-	ns	0.53 ± 0.10	0.52 ± 0.12	-	ns
slgA	6.1 ± 0,1	2.7 ± 0,2	44	0.006	1. 60 ± 0.08	0.56 ± 0.08	58	0.009	1.98 ± 0.60	1.15 ± 0.09	42	0.005
Lf+SC+AS	6.6 ± 0,4	2.7 ± 0,2	59	0.008	0.79 ± 0.04	0.51 ± 0.04	36	0.008	0.70 ± 0.05	0.16 ± 0.05	77	0.007
α-lactoalbumin	7.2 ± 0,4	7.1 ± 0,2	-	ns	0.81 ± 0.05	0.79 ± 0.02	-	ns	0.92 ± 0.60	0.85 ± 0.45	-	ns
fSC	5.8 ± O,5	3.4 ± 0,2	42	0.009	1,3 ± 0.02	0.75 ± 0.04	42	0.003	2.00 ± 0.05	0.84 ± 0.04	58	0.01
Lf	6.2 ± 0,8	3.2 ± 0,1	48	0.002	0.8 ± 0.09	0.42 ± 0.05	48	0.004	1.80 ± 0.02	0.65 ± 0.10	64	0.03

ns = not significative. p = statistical analyses (t-Student independent)

Back to article page

ISSN: 1471-2180

Contact us

General enquiries: journalsubmissions@springernature.com