Figure 2

Ebola virus NP in Vero E6 cells at different phases of the cell cycle. Stereoprojected images of NP (green) that show the three dimensional distribution of the protein in cytoplasmic inclusions in interphase, metaphase and anaphase. The images were reconstituted from a series of fifteen, mathematically deblurred, optical sections 0.3 μm apart. Note that the presence of large inclusions does not interfere with the progression of the cell cycle. Interphase nuclei and chromosomes are stained blue. Pictures were taken 48 hrs post-infection.