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Table 1 Effect of ribavirin and MPA on CBV3 replication in Vero cells and human myocardial fibroblasts (HMF)

From: Mycophenolate mofetil inhibits the development of Coxsackie B3-virus-induced myocarditis in mice

  EC50 (μg/ml)a Yield reductionb (%) MTC (μg/ml)c
  Vero HMF   
MPA 55 80 89 200
Ribavirin 117 250 87 >500
  1. aConcentration of compound that reduces viral induced cytopathic effect by 50% bReduction of virus yield in Vero cells in the presence of 100 μg/ml of either compound cAs determined in Vero cells. Minimal toxic concentration, or correlation required to other normal cell morphology