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Table 1 Effect of ribavirin and MPA on CBV3 replication in Vero cells and human myocardial fibroblasts (HMF)

From: Mycophenolate mofetil inhibits the development of Coxsackie B3-virus-induced myocarditis in mice

 

EC50 (μg/ml)a

Yield reductionb (%)

MTC (μg/ml)c

 

Vero

HMF

  

MPA

55

80

89

200

Ribavirin

117

250

87

>500

  1. aConcentration of compound that reduces viral induced cytopathic effect by 50% bReduction of virus yield in Vero cells in the presence of 100 μg/ml of either compound cAs determined in Vero cells. Minimal toxic concentration, or correlation required to other normal cell morphology
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BMC Microbiology

ISSN: 1471-2180

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