TY - JOUR AU - Delihas, Nicholas PY - 2003 DA - 2003/06/30 TI - Annotation and evolutionary relationships of a small regulatory RNA gene micF and its target ompF in Yersinia species JO - BMC Microbiology SP - 13 VL - 3 IS - 1 AB - micF RNA, a small regulatory RNA found in bacteria, post-transcriptionally regulates expression of outer membrane protein F (OmpF) by interaction with the ompF mRNA 5'UTR. Phylogenetic data can be useful for RNA/RNA duplex structure analyses and aid in elucidation of mechanism of regulation. However micF and associated genes, ompF and ompC are difficult to annotate because of either similarities or divergences in nucleotide sequence. We report by using sequences that represent "gene signatures" as probes, e.g., mRNA 5'UTR sequences, closely related genes can be accurately located in genomic sequences. SN - 1471-2180 UR - https://doi.org/10.1186/1471-2180-3-13 DO - 10.1186/1471-2180-3-13 ID - Delihas2003 ER -