Skip to main content

Table 5 Cefoxitin and Cefepime MIC (by E-test) for selected bacterial isolates

From: Rapid optical determination of β-lactamase and antibiotic activity

S. aureusisolate Cefoxitin MIC (μg/ml) Cefoxitin AS* Cefepime MIC (μg/ml) Cefepime AS**
#1 3.0 ± 0.0 S 3.3 ± 0.3 S
#2 2.2 ± 0.4 S 1.7 ± 0.3 S
#6 3.0 ± 1.0 S 2.8 ± 0.7 S
#18 4.0 ± 1.0 I 2.0 ± 0.5 S
#19 6.0 ± 1.0 I 3.0 ± 0.6 S
#20 20.0 ± 2.3 R 7.0 ± 0.6 S
  1. *The Cefoxitin Antibiotic Susceptibility (AS) was determined using the CLSI Interpretive Criteria for cefoxitin as an oxacillin surrogate [41].
  2. ≤ 4 μg/ml - Susceptible (S), ≥ 8 μg/ml- Resistant (R), values in between Intermediate (I).
  3. **The Cefepime Antibiotic Susceptibility (AS) was determined using the CLSI Interpretive Criteria for cefepime [41].
  4. ≤ 8 μg/ml - Susceptible (S), 16 μg/ml - Intermediate (I), ≥ 32 μg/ml - Resistant (R)
  5. The results are presented as an average of three independent experiments as Average ± Std. Error. The CLSI recommended quality control for MIC for S. aureus, ATCC 29213 (#1) was included each time, and showed MIC within the expected range for cefoxitin (1–4 μg/ml) and cefepime (1–4 μg/ml) respectively.