Skip to main content

Table 3 Distribution of virulence genes and resistance determinants among lineages, CCs and STs of E. faecium

From: Drug-resistant and hospital-associated Enterococcus faecium from wastewater, riverine estuary and anthropogenically impacted marine catchment basin

Lineage/CC/ST MT Isolation site Virulence genes Resistance determinants Transposon genes Plasmidrepgenes Plasmid TAS
    esp/intA fms5 fms17 fms19 fms21 pbp5 GyrA ParC aac(6′)-Ie-aph(2″) ant(6′)-Ia tet(M) tet(L) tet(S) intTn916 tndX rep1 pIP501 rep2 pRE25 rep17 pRUM rep18 pEF418 rep pLG1 rep pMG1 axe-txe ω-ε-ζ relBE
Lineage 17
17 (2) 1, 8 W-EFF 2 2 2 2 2 pbp5-30 S84R R61G S80R    1 1     2 2 1 2 2   1 1  
386 7 W-MOut 1 1 1 1 1      1       1 1 1 1 1   1 1  
Lineage 18
18 (3) 1 (3) D-EFF, W-MOut   3 3 3 1 pbp5-20 S84Y R61G S80I 1 2 3 3     1 2 1   3     
262 10 W-EFF   1 1   1 pbp5-25 S84Y R61G 1   1 1     1 1    1    1  
574 402 VR   1    1          1       1     
Lineage 78
78 (4) 159 (4) W-EFF, W-MOut 4 4 4 4 4 pbp5-28 S84R/Y R61G S80R 2 1 2 2     1 4 4 2 4   4 3  
266 (2) 139 (2) W-INF, D-EFF   2 1 2 2 pbp5-24     1 1    2   1 1 2   2   2   
323 12 D-MOut   1 1 1 1 pbp5-26 wt R61G S80I 1 1 1 1    1 1 1    1     
564 302 D-EFF 1 1 1   1 pbp5-29 S84I R61G S80R   1       1 1 1   1   1 1  
653 302 W-EFF      1 nd S84I R61G S80R   1        1 1       
CC5
29 (2)   W-EFF, W-MOut   2 1   1            2     1     
66   W-MOut   1 1   1       1 1         1   1   
97   W-EFF      1   wt R61G S80R         1     1     
123   W-EFF   1   1    wt R61G         1    1 1     
148   W-MOut   1     pbp5-30 wt R61G S80R   1 1 1    1      1     
168   W-MOut   1 1    pbp5-31     1 1 1   1   1 1 1   1   1   
505   W-EFF   1      wt R61G         1     1     
588   D-MOut   1     pbp5-30     1 1 1    1   1    1     
635   D-EFF    1   1            1     1     
636   W-EFF   1      wt R61G         1         
637   W-EFF   1 1   1   wt R61G         1     1     
638   W-EFF    1     wt R61G S80I         1         
642   W-EFF   1 1 1             1     1     
645   D-EFF   1 1              1     1     1
646   W-EFF   1 1         1    1   1         
649   W-BR   1 1 1   pbp5-32 wt R61G   1               
650 (3)   D-EFF   3 3    pbp5-27     2 2 2   1   1 3        
CC 9
8   D-EFF   1 1 1 1      1 1       1 1 1 1   1   
640   W-EFF   1 1 1 1                1     
CC 22
21   W-EFF    1 1 1      1 1 1   1       1     
22   W-EFF   1 1   1          1 1      1     
25   W-EFF    1   1 pbp5-32 wt R61G 1         1    1     
32 (3)   W-EFF   3 3 1    wt R61G         2     1     
92   W-EFF   1 1   1            1     1     
441   W-EFF   1 1   1       1 1      1    1    1  
533   W-EFF   1                   1 1    
633   W-EFF   1          1   1 1   1         
644   D-EFF   1 1   1            1     1     
CC27
652   W-EFF    1   1            1     1     
CC46
47   VR   1    1            1     1     
69   D-EFF   1 1   1            1 1    1     
CC94
94   W-MOut    1   1            1     1     
361 (4)   D-EFF, D-MOut   3 4 4 4 pbp5-29     1   1       1   4     1
CC296
296   W-EFF   1   1                     
CC639
639   W-EFF   1 1   1            1     1     
CC648
634   W-EFF   1    1            1     1     1
648   W-EFF   1 1   1            1     1     
Doubletons
632   W-MOut   1    1                1     
Singletons
264   W-INF   1   1 1            1 1    1    1  
641   D-EFF   1 1   1                1     
643   W-EFF   1    1            1 1    1    1  
647   W-MOut     1 1            1     1 1    
651   D-EFF    1 1 1             1    1     1
654   VR     1 1            1 1    1     1
All (69)    8 57 49 29 46     6 17 20 17 1 9 4 39 27 14 7 55 2 12 10 5
  1. CC, clonal complex; ST, sequence type; MT, MLVA-type; nd, not determined due to lack of amplification of the pbp5 gene; wt, wild-type; STs associated with MDR phenotype in bold.
  2. Abbreviations of sampling points’ locations and their description provided in Figure 1.