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Figure 5 | BMC Microbiology

Figure 5

From: The antibacterial effect of nitric oxide against ESBL-producing uropathogenic E. coli is improved by combination with miconazole and polymyxin B nonapeptide

Figure 5

The antibacterial effect of DETA/NO in combination with miconazole and polymyxin B nonapeptide in three additional ESBL-producing isolates and in a mutant strain lacking the flavohemoglobin gene ( hmp ). (A) The effect of DETA/NO on bacterial viability when combined with miconazole and polymyxin B nonapeptide (PMBN) in three additional ESBL-producing isolates (ESBL 1, ESBL 6, ESBL 9) after exposure for 24 h. *p < 0.05, **p < 0.01, ***p < 0.001 vs control, †p <0.05 DETA/NO + miconazole + PMBN vs PMBN + miconazole. (B) The effect of DETA/NO on bacterial viability when combined with miconazole and polymyxin B nonapeptide (PMBN) in an hmp-deficient UPEC strain (Δhmp) after exposure for 8 h. Growth is shown as log CFU/ml of treated bacteria or controls (untreated) and compared to the initial starting inoculum. Data are expressed as mean ± SEM of three independent experiments.

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BMC Microbiology

ISSN: 1471-2180

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