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Table 1 S. aureus isolates with and without different types of rearrangement in the spa -gene in community and inpatient samples: formerly non-typeable isolates

From: Prevalence of Staphylococcus aureus protein A (spa) mutants in the community and hospitals in Oxfordshire

Group Community1 Hospital2
  Isolates Individuals Isolates Individuals
  no. % no. % no. % no. %
Total 3,905 100% 442 100% 2,205 100% 1,273 100%
Pure without deletions/insertions or with hidden deletions3 3647 93.4% 334 75.6% 2055 93.2% 1150 90.3%
Mixed with or without deletions and/or rearrangements4 258 6.6% 108 24.4% 150 6.8% 123 9.7%
Formerly non-typeable: i.e. pure with rearrangements affecting standard spa-typing 72 1.8% (from total) 8 1.8% (from total) 14 0.6% (from total) 9 0.7% (from total)
   27.9% (from 12 picks)   7.4% (from12 picks)   9.3% (from 12 picks)   7.3% (from 12 picks)
  1. 1 – nasal swabs collected from individuals recruited in 5 GP practices in Oxfordshire.
  2. 2 – nasal swabs from individuals admitted to the adult ITU, Gerontology and Trauma wards of the Oxford University Hospitals NHS Trust.
  3. 3 – indicates where all samples from an individual were pure using our spa-typing protocol (i.e. were without deletions/insertions or only with hidden deletions) versus any sample did not fall into this category.
  4. 4 –subjected to 12 single colony picks, i.e. 12 sub-colonies analysed from each sample.