High-throughput screening and whole genome sequencing identifies an antimicrobially active inhibitor of Vibrio cholerae

Table 1 Summary of the screening for growth-reducing compounds

Substance collection (number of compounds)	Number of active compounds at different growth reduction rates					∑	Hit rate/1,000
Substance collection (number of compounds)	50-60%	60-70%	70-80%	80-90%	90-100%	∑	Hit rate/1,000
NCH (154)	0	2	1	2	0	5	32.5
Peptide (1,045)	0	0	0	0	0	0	0
LOPAC (1,408)	2	4	0	0	0	6	4.3
VAR (1,936)	1	5	2	8	1	17	8.8
EMC (7,304)	1	0	0	0	0	1	0.1
CDI (16,608)	5	3	5	0	0	13	0.8
28,324						42	1.6

ISSN: 1471-2180