Table 4 O157 proteins up-regulated under anaerobic conditions in uRF, in Experiment II
From: The Escherichia coli O157:H7 bovine rumen fluid proteome reflects adaptive bacterial responses
Protein/Function/Pathway; Name | Accession Number | Molecular Weight ( kDa)1 |
|---|---|---|
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase/Glycolysis/Energy; GpmA | GPMA_ECO57 | 29 kDa |
3-oxoacyl-[acyl-carrier-protein] reductase/Fatty acid biosynthesis; FabG | Q8X8I5_ECO57 | 26 kDa |
3,4-dihydroxy-2-butanone 4-phosphate synthase, Riboflavin (Vitamin B2) biosynthesis/ Cofactor Bisoynthesis; RibB | RIBB_ECO57 | 23 kDa |
30S ribosomal protein S6/Protein Translation; RpsF | RS6_ECO57 | 15 kDa |
4-hydroxy-tetrahydrodipicolinate reductase, Leucine synthesis/Amino acid Biosynthesis; DapB | DAPB_ECO57 | 29 kDa |
50S ribosomal protein L10/Protein Translation; RplJ | RL10_ECO57 | 18 kDa |
50S ribosomal protein L18/Protein Translation; RplR | RL18_ECO57 | 13 kDa |
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta/Fatty acid Biosynthesis; AccD | ACCD_ECO57 | 33 kDa |
Acriflavine resistance protein A/Multidrug efflux system/Transport; AcrA | B5Z3X3_ECO5E | 44 kDa |
ADP-L-glycero-D-manno-heptose-6-epimerase/LPS core Biosynthesis/Heat induced; HldD | HLDD_ECO57 | 35 kDa |
Agmatinase/Polyamine Biosynthesis/Acid Resistance; SpeB | SPEB_ECO57 (+1) | 34 kDa |
AidA-I adhesin-like protein/Adherence; AidA | K0AT24_ECO1C | 141 kDa |
Aminomethyltransferase/Nitrogen, Amino Acid Metabolism; GcvT | GCST_ECO57 | 40 kDa |
Argininosuccinate lyase, Arginine synthesis/ Amino Acid Biosynthesis; ArgH | ARLY_ECO57 | 50 kDa |
AsmA protein/LPS Biogenesis; AsmA | B5YUC4_ECO5E (+5) | 69 kDa |
Aspartate carbamoyltransferase regulatory chain/Nucleotide Biosynthesis; PyrI | PYRI_ECO57 | 17 kDa |
Aspartate--tRNA ligase/Aminoacyl-tRNA Biosynthesis; AspS | SYD_ECO57 (+1) | 66 kDa |
Aspartate-semialdehyde dehydrogenase/Amino acid Biosynthesis; AsD | DHAS_ECO57 | 40 kDa |
ATP synthase subunit b/Energy Production; AtpF | ATPF_ECO57 | 17 kDa |
ATP-dependent helicase/DNA Replication, Repair; HrpB | Q8X904_ECO57 (+1) | 91 kDa |
ATP-dependent protease subunit/Proteolysis; HslV | HSLV_ECO57 | 19 kDa |
Bacterioferritin/Iron storage and Transport; BfR | Q8X890_ECO57 | 18 kDa |
Bacteriophage replication gene A protein/Predicted Phage replication; ECH74115_3058 | B5YUH3_ECO5E | 86 kDa |
Beta-D-glucoside glucohydrolase, degradation of small carbon compunds/Biosyntheis of secondary metabolites; BglX | Q8X668_ECO57 | 83 kDa |
Bifunctional N-acetylglucosamin-1-phosphate-uridyl transferase/Cell Wall Synthesis; GlmU | GLMU_ECO57 (+2) | 49 kDa |
Bifunctional purine biosynthesis protein/Purine Biosynthesis; PurH | PUR9_ECO57 | 57 kDa |
Biofilm regulator/Biofilms, Adherence; BssR | BSSR_ECO57 | 15 kDa |
Biosynthetic arginine decarboxylase/Polyamine Biosynthesis, Acid Resistance; SpeA | SPEA_ECO57 | 74 kDa |
Biotin carboxyl carrier protein of acetyl-CoA carboxylase/Fatty Acid Biosynthesis; AccB | BCCP_ECO57 (+8) | 17 kDa |
Branched-chain-amino-acid aminotransferase/Amino acid Transport and Metabolism; IlvE | ILVE_ECO57 | 34 kDa |
Catabolite repression sensor kinase for PhoB alternative sensor for pho regulon/Global Regulaor; CreC | Q8XB07_ECO57 | 52 kDa |
Catalase-peroxidase 1/Prevent Cell, DNA damage/Oxidative Stress; KatG1 | KATG1_ECO57 | 80 kDa |
Cell Division protein; ZapB | ZAPB_ECO5E (+8) | 9 kDa |
Cellulose synthase subunit/Biofilms, Adherence; BcsC | C8TYF1_ECO10 (+2) | 126 kDa |
Chromosome partition protein/Cell Division; MukB | MUKB_ECO57 (+2) | 170 kDa |
Curli production assembly/transport subunit/Biofilms, Adherence; CsgG | B5YVQ8_ECO5E (+1) | 31 kDa |
Cyclic pyranopterin monophosphate synthase accessory protein/Cofactor Biosynthesis; MoaC | MOAC_ECO57 | 17 kDa |
Cytidylate kinase/Nucleotide Biosynthesis; Cmk | KCY_ECO57 | 25 kDa |
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase | ||
Complex/Energy Metabolism; SucB | ODO2_ECO57 | 44 kDa |
Dihydroorotase/Nucleotide Biosynthesis; PyrC | PYRC_ECO57 | 39 kDa |
DNA helicase/DNA Replication, Transcription; RecB | Q8X6M9_ECO57 | 134 kDa |
DNA invertase from prophage CP-933H/DNA Replication; PinH | Q8X7L1_ECO57 | 22 kDa |
DNA topoisomerase IV subunit B/DNA Replication; ParE | Q8XBQ4_ECO57 | 70 kDa |
DNA-directed RNA polymerase subunit alpha/DNA Transcription; RpoA | RPOA_ECO57 | 37 kDa |
DNA-directed RNA polymerase subunit beta/DNA Transcription; RpoB | RPOB_ECO57 | 151 kDa |
DNA-directed RNA polymerase subunit omega/DNA Transcription; RpoZ | RPOZ_ECO57 | 10 kDa |
Elongation factor P-like protein/Translation, Protein synthesis; YeiP | EFPL_ECO57 | 22 kDa |
Evolved beta-D-galactosidase alpha subunit/Degradation of small carbon compounds; EbgA | Q8XAM9_ECO57 | 119 kDa |
Ferritin-1/Iron Uptake and Storage; FtnA | FTNA_ECO57 | 19 kDa |
Fimbrial usher family protein/Chaperone/Transport; ECH74115_2118 | B5Z1W3_ECO5E (+5) | 81 kDa |
Formate dehydrogenase-O major subunit/Energy Metabolism, Anaerobic Respiration; FdoH | Q7A9A6_ECO57 (+1) | 113 kDa |
Fructose-bisphosphate aldolase, class 1/Glycolysis, Gluconeogensis; FbaB | B5YV44_ECO5E (+1) | 38 kDa |
Galactose-1-phosphate uridylyltransferase/Galactose Metabolism; GalT | Q8X943_ECO57 | 40 kDa |
Glucans biosynthesis protein G/Osmotic Adaptation; MdoG | OPGG_ECO5E | 59 kDa |
Glutamate--tRNA ligase/Amino acyl tRNA synthesis; GltX | SYE_ECO57 | 54 kDa |
Glutamine synthetase/Amino acid Biosynthesis; GlnA | GLNA_ECO57 | 52 kDa |
Glutathione synthetase/Cofactors, carriers Biosynthesis; GshB | GSHB_ECO57 | 35 kDa |
Glycerol kinase/Glycerolipid Metabolism; GlpK | GLPK_ECO57 | 56 kDa |
Glycine dehydrogenase [decarboxylating]/Amino acid Metabolism; GcvP | GCSP_ECO57 | 104 kDa |
GMP synthase [glutamine-hydrolyzing]/Nucleotide Biosynthesis; GuaA | GUAA_ECO57 | 59 kDa |
GTPase-activating protein/Transcriptional Activator; YihI | YIHI_ECO57 | 19 kDa |
Guanylate kinase/Nucleotide Biosynthesis; GmK | KGUA_ECO57 (+2) | 24 kDa |
Hemin import ATP-binding protein/Transport; HmuV | HMUV_ECO57 | 29 kDa |
Histidine--tRNA ligase/Amino acyl tRNA synthesis; HisS | SYH_ECO57 | 47 kDa |
HTH-type transcriptional regulator/Maltooligosaccharide Uptake and Metabolism; MalT | MALT_ECO57 | 103 kDa |
Hydrogenase-2 large chain/Energy Metabolism/Anaerobic Respiration; HybC | MBHM_ECO57 | 62 kDa |
Hydroxyacylglutathione hydrolase/Pyruvate Metabolism; GloB | GLO2_ECO57 | 28 kDa |
Inosine-5′-monophosphate dehydrogenase/Nucleotide Biosynthesis; GuaB | B5Z0X7_ECO5E | 54 kDa |
Iron-sulfur cluster insertion protein/Growth using alternate electron acceptors; ErpA | ERPA_ECO57 | 12 kDa |
Long-chain fatty acid transport protein/Transport; FadL | FADL_ECO57 | 49 kDa |
Low-affinity putrescine importer/Transport; PlaP | PLAP_ECO57 | 50 kDa |
LPS-assembly lipoprotein/LPS Biogenesis; LptE | LPTE_ECO57 | 21 kDa |
Macrolide export ATP-binding/permease protein/Transport; MacB | MACB_ECO57 | 71 kDa |
Major outer membrane lipoprotein/Membrane Integrity; Lpp | LPP_ECO57 | 8 kDa |
Mannitol-1-phosphate 5-dehydrogenase/Fructose, Mannose Metabolism; MtlD | MTLD_ECO57 | 41 kDa |
Membrane, TerC family/CBS/transporter associated protein/Transport/Tellurium Resistance; TerC | B5YUC1_ECO5E (+6) | 59 kDa |
Methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor/Chemotaxis; Trg | C8U899_ECO10 | 59 kDa |
Minor curlin protein/Biofilms, Adherence; CsgB | B5YVR3_ECO5E (+1) | 17 kDa |
Multiple Resistance and pH adaptation protein, antiporter/Transport; Mrp | B5YV63_ECO5E (+1) | 40 kDa |
Multidrug resistance efflux protein/Transport; MdtC | C8TU07_ECO26 (+2) | 111 kDa |
Multiphosphoryl transfer protein/Fructose, Mannose Metabolism; FruB | PTFAH_ECO57 | 40 kDa |
N-acetylglucosamine-6-phosphate deacetylase/LPS Biosynthesis; NagA | NAGA_ECO57 | 41 kDa |
NADH-quinone oxidoreductase subunit C/D/Electron transfer/Energy Metabolism; NuoC | NUOCD_ECO57 (+2) | 69 kDa |
NifU-like protein/Energy Production, Conversion; NifU | NIFU_ECO57 | 14 kDa |
Non-LEE-encoded type III secreted effector; EspX7 | C6URC5_ECO5T (+2) | 73 kDa |
Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein/Transport; OppA | B5YYE8_ECO5E | 63 kDa |
Osmotically-inducible lipoprotein E/Global Regulator; OsmE | OSME_ECO57 | 12 kDa |
Outer membrane lipoprotein/Cell Envelope Biogenesis; SlyB | SLYB_ECO57 | 16 kDa |
Outer membrane protein, porin, receptor, integrity/Membrane Stability; OmpA | B5YT87_ECO5E | 38 kDa |
Outer membrane protein assembly factor/Membrane Assembly, Antibiotic Resistance; BamA/YaeT | BAMA_ECO57 | 91 kDa |
Outer membrane protein assembly factor/Membrane Assembly, Antibiotic Resistance; BamD/YfiO | BAMD_ECO57 | 28 kDa |
Outer membrane protein, efflux protein/Transport; TolC | B5YR81_ECO5E (+2) | 54 kDa |
Outer membrane protein W/Outer Membrane Biogenesis; OmpW/YciD | Q8XCB6_ECO57 | 23 kDa |
Oxidoreductase subunit/Oxidative Stress; DmsA_YnfF | C6UV29_ECO5T (+6) | 90 kDa |
Penicillin-binding protein activator/Lipid binding/Putative Adhesin; LpoB/YcfM | LPOB_ECO57 | 23 kDa |
Peptidase B/Protein Metabolism; PepB | PEPB_ECO57 | 46 kDa |
Peptide chain release factor 1/Protein Translation; PrfA | RF1_ECO57 | 41 kDa |
Peptidyl-prolyl cis-trans isomerase A/Post-translational Modification; PpiA | PPIA_ECO57 | 20 kDa |
Peptidyl-prolyl cis-trans isomerase/Post-translational Modification; FklB | B5Z2L4_ECO5E (+2) | 22 kDa |
Periplasmic binding protein for nickel/Amino acid Transport and Metabolism; NikA | Q8X5U3_ECO57 (+1) | 59 kDa |
Phenylalanine--tRNA ligase alpha subunit/Amino acyl tRNA synthesis; PheS | SYFA_ECO57 (+2) | 37 kDa |
Phenylalanine--tRNA ligase beta subunit/Amino acyl tRNA synthesis; PheT | SYFB_ECO57 | 87 kDa |
Poly (A) polymerase I/DNA Transcription; PcnB | PCNB_ECO57 (+3) | 54 kDa |
Proline--tRNA ligase/Amino acyl tRNA synthesis; ProS | SYP_ECO57 | 64 kDa |
Protease IgA1, Serine protease/Protection; EspP | K0AWD8_ECO1C | 146 kDa |
Protein elaB/Uncharacterized; ElaB | ELAB_ECO57 | 11 kDa |
Protein grpE, prevents aggregation of denatured proteins/ Heat and Hyperosmotic Shock-Related; GrpE | C8U980_ECO10 (+2) | 22 kDa |
Protein translocase subunit/Transport; SecD | SECD_ECO57 | 67 kDa |
PTS system, mannose-specific transporter subunit IID/Transport; ManZ | B5YQW0_ECO5E (+1) | 31 kDa |
Putative anaerobic dimethyl sulfoxide reductase chain A; DmsA_YnfE | Q7ABM3_ECO57 (+1) | 88 kDa |
Putative DNA replication factor encoded within cryptic prophage CP-933P/Hypothetical; Z6069 | Q8XAD9_ECO57 | 28 kDa |
Putative endopeptidase of prophage CP-933X/Hypothetical; Z1877 | Q8X704_ECO57 | 12 kDa |
Putative carboxypeptidase/Hypothetical; YagX | Q8X6I4_ECO57 (+1) | 91 kDa |
Putative lipoprotein induced during stationary phase/Stress Response; YbjP | Q8X6N7_ECO57 (+1) | 19 kDa |
Putative homeobox protein/Regulator; YbgS | Q8X948_ECO57 | 13 kDa |
Putative lipoprotein/Membrane protein; LppC | B5YUN1_ECO5E | 20 kDa |
Putative membrane protein, peptidase/Uncharacterized; YibP | Q8XDE2_ECO57 | 47 kDa |
Putative multimodular enzyme/Energy Metabolism; Z3719 | Q8XBF4_ECO57 | 82 kDa |
Putative pectinesterase, localizes to cellular poles/Membrane protein; YbhC | Q8X891_ECO57 | 46 kDa |
Putative replicase/DNA Replication; Z5187 | Q8XBZ7_ECO57 | 37 kDa |
Pyridoxine 5′-phosphate synthase/Vitamin B6 (Pyridoxine) synthesis; PdxJ | PDXJ_ECO57 | 26 kDa |
Pyruvate dehydrogenase (Dihydrolipoyltransacetylase component)/Energy Metabolism; AceF | Q8X966_ECO57 | 66 kDa |
Pyruvate oxidase/Degradation of small carbon compunds; PoxB | Q8X6L4_ECO57 | 62 kDa |
RNase E/RNA Degradation; RnE | Q8X8J5_ECO57 | 118 kDa |
Serine protease/Protection; DegP | B5Z0E1_ECO5E (+1) | 49 kDa |
Serine endoprotease/Protection; DegQ | Q8X9F1_ECO57 | 47 kDa |
Single-stranded DNA-binding protein/DNA Replication; SsB | SSB_ECO57 | 19 kDa |
Soluble cytochrome, electron transport/Energy Metabolism; CybC | C562_ECO57 (+4) | 14 kDa |
Spermidine/putrescine import ATP-binding protein/Transport; PotA | POTA_ECO57 | 43 kDa |
Stringent starvation protein A, stationary phase induced acid tolerance/Global Regulator; SspA | SSPA_ECO57 | 24 kDa |
Stringent starvation protein B, ClpXP protease specificity enhancer/Global Regulator; SspB | SSPB_ECO57 | 18 kDa |
Succinate dehydrogenase flavoprotein subunit/Energy Metabolism; SdhA | DHSA_ECO57 | 64 kDa |
Tat-linked quality control protein/DNAse activity; TatD | Q8X8J6_ECO57 | 30 kDa |
Thiosulfate sulfurtransferase/Anaerobic Respiration, Energy Metabolism; GlpE | C8TJL4_ECO26 (+2) | 12 kDa |
Threonine deaminase (Dehydratase)/Amino acid Biosynthesis; IlvA | Q8X467_ECO57 | 56 kDa |
Transcription termination/antitermination protein/Modulates DNA Transcription; NusG | NUSG_ECO57 | 21 kDa |
Transcriptional regulatory protein/Envelope Stress Response Protein/Downregulates LEE; CpxR | CPXR_ECO57 | 26 kDa |
Transketolase 1, thiamin-binding/Non-oxidative Metabloism; TktA | C8TGU9_ECO26 | 72 kDa |
Transketolase 2 isozyme, stationary phase induced/Non-oxidative Metabolism; TktB | Q8XBF1_ECO57 (+6) | 73 kDa |
Translation initiation factor IF-2/Protein Translation; InfB | IF2_ECO57 | 97 kDa |
Trigger factor/Cell division; TiG | TIG_ECO57 (+1) | 48 kDa |
Tryptophanase/Tryptophan Metabolism, Indole Production; TnaA | TNAA_ECO57 | 53 kDa |
Type II secretion pathway related protein/Transport; EtpE | O82884_ECO57 | 56 kDa |
Tyrosine-protein kinase/Downregulates colanic acid production; WzC | WZC_ECO57 | 79 kDa |
Uncharacterized protein/Hypothetical; ECs1547 | Q8X3G9_ECO57 (+1) | 17 kDa |
Uncharacterized protein/Hypothetical; ECs2891 | Q8X7H8_ECO57 | 14 kDa |
Uncharacterized protein/Hypothetical; ECs2991 | Q8X2Z1_ECO57 | 10 kDa |
Putative oxidative stress defense protein/ Oxidative Stress; YggE | YGGE_ECO57 | 27 kDa |
Uncharacterized protein/Membrane Protein; YqjD | YQJD_ECO57 | 11 kDa |
UPF0042 nucleotide-binding protein/putative ATPase; YhbJ | YHBJ_ECO57 | 32 kDa |
UPF0092 membrane protein, translocase/Transport; YajC | YAJC_ECO57 | 12 kDa |
UPF0337 protein, putative stress response protein/Osmotic Shock; YjbJ | YJBJ_ECO57 | 8 kDa |
UPF0352 protein/Uncharacterized; YejL | YEJL_ECO57 | 8 kDa |
Uridylate kinase/Nucleotide Interconversion; PyrH | PYRH_ECO57 | 26 kDa |
Valine--tRNA ligase/Amino acyl tRNA Biosynthesis; ValS | SYV_ECO57 | 108 kDa |