Skip to main content

Table 3 Genes differentially expressed in H. influenzae R3264 at pH 8.0 compared to pH 6.8

From: There is a specific response to pH by isolates of Haemophilus influenzae and this has a direct influence on biofilm formation

Genes up-regulated at pH 8.0 compared to 6.8
Iron uptake genes
Gene Log2fold p -value FDR Comment
hitA 1.76 9.65×10-12 2.46×10-9 Iron uptake ABC, periplasmic domain
hitB 1.31 8.77×10-7 1.11×10-4 Iron uptake ABC, permease domain
tbp2 1.54 2.92×10-5 2.74×10-3 Iron-binding OM receptor
tbp1 1.49 3.53×10-7 5.26×10-5 Transferrin binding protein
h×uB 1.02 8.62×10-5 7.32×10-3 Heme-hemopexin utilization protein
Metabolic genes
Gene Log 2 fold p -value FDR Comment
glpB 1.08 5.35×10-5 4.77×10-3 Glycerol metabolism
Genes of unknown function
Gene Log 2 fold p -value FDR Comment
HI0997 1.34 8.95×10-4 5.51×10-2 Hypothetical protein
HI1427 1.31 4.17×10-7 5.72×10-5 Transmembrane protein
Genes down-regulated at pH 8.0 compared to 6.8
Gene Log 2 fold p -value FDR Comment
HI1349 -1.23 5.14×10-6 5.10×10-4 Ferritin
ahpD -1.72 1.24×10-7 2.01×10-5 Stress response