There is a specific response to pH by isolates of Haemophilus influenzae and this has a direct influence on biofilm formation

Table 1 Growth rates of H. influenzae isolates grown at different pH

Strain	Type	pH 6.8	pH 7.0	pH 8.0
Rd KW20	Serotype d, non-capsular	0.414 ± 0.08*	0.515 ± 0.10	0.443 ± 0.12
86-028NP	NTHi, OM	0.330 ± 0.09	0.483 ± 0.05	0.435 ± 0.04
R2846	NTHi, OM	0.405 ± 0.11	0.587 ± 0.04	0.477 ± 0.09
NTHi-1	NTHi, lung	0.412 ± 0.07	0.243 ± 0.01	0.410 ± 0.08
R2866	NTHi, blood	0.291 ± 0.04	0.194 ± 0.01	0.300 ± 0.05
285	NTHi, OM	0.293 ± 0.05	0.367 ± 0.07	0.422 ± 0.10
C486	NTHi, OM	0.480 ± 0.03	0.446 ± 0.04	0.554 ± 0.05
Hi667	NTHi, OM	0.281 ± 0.04	0.338 ± 0.01	0.234 ± 0.02
Eagan	Serotype b, CSF	0.358 ± 0.03	0.386 ± 0.07	0.391 ± 0.08
R3264	NTHi, middle ear of healthy child	0.256 ± 0.04	0.303 ± 0.03	0.236 ± 0.06
86-66MEE	NTHi, OM	0.295 ± 0.04	0.258 ± 0.02	0.200 ± 0.04

ISSN: 1471-2180