Figure 6From: DevR (DosR) mimetic peptides impair transcriptional regulation and survival of Mycobacterium tuberculosis under hypoxia by inhibiting the autokinase activity of DevS sensor kinase Cytotoxicity of peptides. Percentage cytotoxicity due to exposure to peptides was assessed in HepG2 and CHO cell lines using the MTT assay. The cells were exposed to DevRS A-ext and DevRS D peptides at 2.5 mM and 5 mM concentration in 96-well plate format for 48 h. Percentage cytotoxicity is shown with respect to the DMSO control as mean ± SD for duplicate values.Back to article page