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Figure 5 | BMC Microbiology

Figure 5

From: DevR (DosR) mimetic peptides impair transcriptional regulation and survival of Mycobacterium tuberculosis under hypoxia by inhibiting the autokinase activity of DevS sensor kinase

Figure 5

Peptides inhibit hypoxic survival of M. tb . Effect of peptides on viability of M. tuberculosis under hypoxic and aerobic conditions as determined by CFU (A), Resazurin reduction assays HyRRA – hypoxic conditions (B) and REMA- aerobic conditions (C). The data represents the mean and standard deviation of two independent experiments. '0’ on top of some of the bars indicates lack of detectable inhibition. *denotes p value of <0.05 for the difference in peptide-mediated inhibition of viability under hypoxia vs. aerobic conditions by CFU and/Resazurin reduction assays based on a Student’s t-test.

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