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Table 2 Minimum inhibitory concentrations (MICs) of curcumin, epigallocatechin gallate and combinations of both compounds and fractional inhibitory concentration indexes (FICIs) versus Acinetobacter baumannii

From: In vitro activity of curcumin in combination with epigallocatechin gallate (EGCG) versus multidrug-resistant Acinetobacter baumannii

Isolate MICs in monotherapy (μg/mL) MICs in combination (μg/mL) FICIs
CCM EGCG CCM EGCG
AB 19606 >256 1024 4 256 0.258 (S)
AB 14 >256 1024 4 512 0.508 (Ad)
AB 16 >256 1024 32 512 0.56 (Ad)
AB 186 >256 512 64 128 0.38 (S)
AB 202 >256 1024 64 512 0.63 (Ad)
AB 205 >256 1024 4 512 0.508 (Ad)
AB 292 >256 1024 4 256 0.258 (S)
AB 306 >256 128 4 32 0.258 (S)
AB 308 >256 256 4 64 0.258 (S)
  1. MICs were within +/-1 dilution on replicate tests. CCM = curcumin, EGCG = epigallocatechin gallate, S = synergy, Ad = additive effect.