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Table 2 Minimum inhibitory concentrations (MICs) of curcumin, epigallocatechin gallate and combinations of both compounds and fractional inhibitory concentration indexes (FICIs) versus Acinetobacter baumannii

From: In vitro activity of curcumin in combination with epigallocatechin gallate (EGCG) versus multidrug-resistant Acinetobacter baumannii

Isolate

MICs in monotherapy (μg/mL)

MICs in combination (μg/mL)

FICIs

CCM

EGCG

CCM

EGCG

AB 19606

>256

1024

4

256

0.258 (S)

AB 14

>256

1024

4

512

0.508 (Ad)

AB 16

>256

1024

32

512

0.56 (Ad)

AB 186

>256

512

64

128

0.38 (S)

AB 202

>256

1024

64

512

0.63 (Ad)

AB 205

>256

1024

4

512

0.508 (Ad)

AB 292

>256

1024

4

256

0.258 (S)

AB 306

>256

128

4

32

0.258 (S)

AB 308

>256

256

4

64

0.258 (S)

  1. MICs were within +/-1 dilution on replicate tests. CCM = curcumin, EGCG = epigallocatechin gallate, S = synergy, Ad = additive effect.