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Table 1 Permeability coefficients for metabolites and oxygen (PmO 2 ) in presence of a polyamide membrane (pore size 0.2 μm) with and without mucus layer (200 μm) (n = 2)

From: The HMI™ module: a new tool to study the Host-Microbiota Interaction in the human gastrointestinal tract in vitro

Polyamide membrane

FITC dextran

Oxygen

 

4 kDa

20 kDa

150 kDa

 

With mucus

2.4 ± 10−6

2.5 ± 10−7

7.1 ± 10−9

2.5 ± 10−4

Without mucus

5.6 ± 10−6

4.1 ± 10−7

6.5 ± 10−7

NDa

  1. aND = not determined.
  2. Data are expressed as cm sec−1. The permeation coefficient was lower in presence of the mucus and with the increase of the FITC dextran kDa.