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Table 2 In vitro effects of pH, lactic and acetic acids on Pseudomonas aeruginosa PAO1 growth

From: Screening of Lactobacillus spp. for the prevention of Pseudomonas aeruginosa pulmonary infections

Acid concentrations (mM)

OD595nmof P. aeruginosa at different pH and acid concentrations*

Lactic acid

pH 7

pH 6

pH 5

pH 4

0

0.60 ± 0.03

0.62 ± 0.01

0.43 ± 0.02

0.01 ± 0.00

50

0.74 ± 0.06

0.81 ± 0.11

0.47 ± 0.19

0.12 ± 0.01

100

0.65 ± 0.02

0.65 ± 0.02

0.23 ± 0.07

0.12 ± 0.01

Acetic acid

pH 7

pH 6

pH 5

pH 4

0

0.60 ± 0.03

0.62 ± 0.01

0.43 ± 0.02

0.01 ± 0.00

12.5

0.70 ± 0.06

0.58 ± 0.02

0.38 ± 0.27

0.12 ± 0.01

25

0.63 ± 0.06

0.65 ± 0.09

0.11 ± 0.01

0.12 ± 0.00

50

0.56 ± 0.02

0.26 ± 0.07

0.11 ± 0.01

0.12 ± 0.01

100

0.77 ± 0.14

0.10 ± 0.01

0.11 ± 0.01

0.13 ± 0.01

  1. * Each value is the mean of triplicates ± SD (ANCOVA), P. aeruginosa was incubated in BHI medium for 22 h in presence of different acid concentrations (acetic, lactic acid or HCl).