Table 4 Antibiotic resistance genes in M.yannicii PS01 genome

Beta-lactams

ampC

323

Beta-lactamase class C

Isoptericola variabilis 225

56.5

5.00E-114

ampC

422

Beta-lactamase class C

Microbacterium testaceum StLB037

54

1.00E-123

ampC

364

Beta-lactamase class C

Paenibacillus mucilaginosus KNP414

37.8

3.00E-59

ampC

338

Beta-lactamase class C

Arthrobacter aurescens TC1

41.9

4.00E-67

-

558

Predicted hydrolase of the metallo-beta-lactamase superfamily

Microbacterium laevaniformans OR221

88.8

0

-

212

Predicted Zn-dependent hydrolases of the beta-lactamase fold

Microbacterium testaceum StLB037

66.9

2.00E-100

elaC

290

Metal-dependent hydrolases of the beta-lactamase superfamily III

Saccharomonospora paurometabolica YIM 90007

46.6

2.00E-74

penP

279

Beta-lactamase class A

Microbacterium testaceum StLB037

77.3

7.00E-146

-

615

Beta-lactamase domain protein

Kribbella flavida DSM 17836

44.2

3.00E-148

-

626

Beta-lactamase domain protein

Mycobacterium rhodesiae JS60

66.8

0

-

524

Zn-dependent hydrolase of the beta-lactamase fold

Microbacterium testaceum StLB037

83.8

0.00E+00

Aminoglycoside

aph

51

Aminoglycoside phosphotransferase

Microbacterium laevaniformans OR221

72

2.00E-17

-

435

Predicted aminoglycoside phosphotransferase

Microbacterium testaceum StLB037

61

3.00E-130

-

292

Aminoglycoside phosphotransferase

Micromonospora lupini str. Lupac 08

55.9

3.00E-95

-

308

Aminoglycoside phosphotransferase

Streptosporangium roseum DSM 43021

43.8

7.00E-71

-

350

Aminoglycoside phosphotransferase

Cellulomonas fimi ATCC 484

60.4

1.00E-125

Macrolides

-

461

Macrolide-efflux protein

Beutenbergia cavernae DSM 12333

65.4

2.00E-166

Fluoroquinolones

gyrA mutated: S83A

883

DNA gyrase subunit A (EC 5.99.1.3)

Microbacterium testaceum StLB037

87.7

0

parC mutated: S80A

819

Topoisomerase IV subunit A (EC 5.99.1.-)

Microbacterium testaceum StLB037

82.7

0

Sulfamides

dhps

281

Dihydropteroate synthase

Microbacterium laevaniformans OR221

71.6

2.00E-122

Multidrug Efflux pumps

corC

450

Magnesium and cobalt efflux protein

Microbacterium testaceum StLB037

78.4

0

kefA

373

Potassium efflux system

Microbacterium laevaniformans OR221

74.7

0

-

548

Putative MFS Superfamily multidrug efflux transporter

Nocardia cyriacigeorgica GUH-2

72.8

0

-

513

putative efflux MFS permease

Microbacterium laevaniformans OR221

78.8

0

-

212

Putative threonine efflux protein

Microbacterium testaceum StLB037

61.6

1.00E-80

-

1275

RND multidrug efflux transporter; Acriflavin resistance protein

Microbacterium laevaniformans OR221

78.1

0

-

426

antibiotic efflux protein

Microbacterium laevaniformans OR221

83.5

0

-

526

probable multidrug resistance transporter, MFS family

Cellulomonas fimi ATCC 484

68.8

0

-

474

Inner membrane component of tripartite multidrug resistance system

Arthrobacter aurescens TC1

68.2

0

-

354

ABC-type multidrug transport system, ATPase component

Saccharopolyspora erythraea NRRL 2338

58.8

1.00E-119

bcr/cflA

417

Multidrug resistance transporter, Bcr/CflA family

Brachybacterium paraconglomeratum LC44

68.5

1.00E-154

-

519

multidrug resistance protein

Arthrobacter aurescens TC1

54.2

8.00E-177

-

332

ABC-type multidrug transport system, ATPase component

Microbacterium laevaniformans OR221

72.2

6.00E-142

-

264

ABC-type multidrug transport system, ATPase component

Microbacterium testaceum StLB037

75

1.00E-143

-

303

ABC-type multidrug transport system, ATPase component

Paenibacillus curdlanolyticus YK9

59.5

7.00E-110

-

273

ABC-type multidrug transport system, permease component

Paenibacillus curdlanolyticus YK9

67.7

3.00E-121

-

306

ABC-type multidrug transport system, ATPase component

Clavibacter michiganensis subsp. michiganensis NCPPB 382

60.8

3.00E-107