CusA
| M271 | M391 | M403 | M410 | M486 | M501 | M573 | M623 | M672 | M755 | M1009 | D405 | E939 | K984 |
CzrA
| L301a | M420 | I430 | I437 | L512 | V527 | Q598 | A648 | E699 | A782 | Q1031 | D432 | L972 | V1006 |
NczA
| L291 | M410 | I420 | I427 | L502 | V517 | H588 | V638 | E689 | V722 | Q1020 | D422 | L961 | V995 |
Residue conserved
b
| --- (L) | M (M) | I/L (I/L) | I/V (I/V) | L (L) | ---(V/I) | --- (−−-) | --- (−−-) | E (E) | --- (−−-) |
Q
(
Q
)
|
D
(
D
)
|
L
(
L
)
| V(V/I) |
- aThe numbers correspond to the positions in C. crescentus CzrA and NczA proteins, respectively. The correspondence was determined by sequence alignment made using the PHYRE2 program [44].
- b Conservation profile within the CzrA-like proteins and in the NczA-like proteins (in parentheses). A conserved residue was considered the residue most prevalent (more than 75% conserved) in that position within the CzcA orthologous groups. In bold and italic are shown the residues absolutely conserved and ----- is not conserved.