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Table 1 MICs of different antibiotics towards P. aeruginosa PA14 WT, PA14 typA mutant and complemented mutant PA14 typA ::p typA +a

From: TypA is involved in virulence, antimicrobial resistance and biofilm formation in Pseudomonas aeruginosa

  MIC (μg/ml)
Antibiotic PA14 WT PA14typA PA14typA ::ptypA +
Ciprofloxacin 0.03 0.03 0.03
Meropenem 2 1 2
Ceftazidime 4 2 4
Tetracycline 8 4 8
Tobramycin 0.25 0.25 0.25
Polymyxin B 0.5 0.25 0.5
Colistin 0.25 0.125 0.25
LL-37 16 16 16
  1. aMICs were determined by serial 2-fold dilutions in MH-medium. The MIC represents the concentration at which no growth was visually observed after 24 h of incubation at 37°C. The values shown are the modes of 4 to 6 independent experiments.