Skip to main content
Figure 3 | BMC Microbiology

Figure 3

From: Advanced application of bovine intestinal epithelial cell line for evaluating regulatory effect of lactobacilli against heat-killed enterotoxigenic Escherichia coli-mediated inflammation

Figure 3

Evaluation of the immunomodulatory activity of lactobacilli. (A) Bovine intestinal epithelial (BIE) cells were pre-treated with immunobiotic Lactobacillus jensenii TL2937 or Pam3CSK4 for 12, 24 or 48 hours, stimulated with heat-stable ETEC PAMPs and then the expression of MCP-1, IL-6 and IL-8 was studied at hour twelve post-stimulation. Significantly different from ETEC Control *(P<0.05). (B) Levels of MCP-1 and IL-6 proteins. BIE cells were pre-treated with Lactobacillus casei OLL2768 or L. casei MEP221108 for 48 hours and the stimulated with heat-stable ETEC PAMPs and then levels of MCP-1 and IL-6 was studied at hour twelve post-stimulation. Significantly different from ETEC Control *(P<0.05).

Back to article page