Decontamination of mycoplasma-contaminated Orientia tsutsugamushistrains by repeating passages through cell cultures with antibiotics

Table 1 Minimum inhibitory concentrations (MICs) of antibiotics used in this study

Antibiotics	Drug class	MICs againstOrientia^a)	MICs against mycoplasmas^b)
Lincomycin	Lincosamide	No available data	0.25–2 μg/mL
Ciprofloxacin	New Quinolone	6.25–25 μg/mL	0.125–2 μg/ml
Gentamicin	Aminoglycoside	No available data^c)	2.5–500 μg/mL
Kanamicin	Aminoglycoside	No available data	2.5–500 μg/mL
Minocycline	Tetracycline	0.024–0.195 μg/mL	0.016–32 μg/mL

MICs were obtained from previous reports. a) from [8] and b) from [5–7].
c) Gentamycin was not effective against Orinetia tsutsugamushi in a mouse model [25].

ISSN: 1471-2180