Skip to main content


Table 7 MFS members in Sco and Mxa

From: Comparative genomics of transport proteins in developmental bacteria: Myxococcus xanthus and Streptomyces coelicolor

TC Number Family name Known substrate range Sco Mxa
2.A.1.1 The Sugar Porter (SP) Family sugar and sugar derivative (uniport; symport); urate (antiport) 2  
2.A.1.2 The Drug:H+ Antiporter-1 (12 Spanner) (DHA1) Family drug, polyamine, neurotransmitter, sugar, nucleobase/side, siderophore, lipid (antiport); vitamin (symport) 12 9
2.A.1.3 The Drug:H+ Antiporter-2 (14 Spanner) (DHA2) Family drug, boron, bile acid, parquot, fatty acid, siderophore, amino acid (antiport); pyrimidine (symport) 49 6
2.A.1.4 The Organophosphate:Pi Antiporter (OPA) Family carbohydrate phosphate (antiport)   1
2.A.1.6 The Metabolite:H+ Symporter (MHS) Family organic acid/base, sugar acid (symport) 6 1
2.A.1.8 The Nitrate/Nitrite Porter (NNP) family nitrate/nitrite (symport/antiport) 2 1
2.A.1.11 The Oxalate:Formate Antiporter (OFA) Family oxalate/formate (antiport) 3  
2.A.1.14 The Anion:Cation Symporter (ACS) Family organic and inorganic anion, peptide, vitamin, amino acid, nucleotide (uniport; symport) 3  
2.A.1.15 The Aromatic Acid:H+ Symporter (AAHS) Family aromatic acid, vitamin (symport) 3 1
2.A.1.17 The Cyanate Porter (CP) Family cyanate, glucose (symport) 3  
2.A.1.21 The Drug:H+ Antiporter-3 (12 Spanner) (DHA3) Family drug, siderophore (antiport) 6 7
2.A.1.24 The Unknown Major Facilitator-1 (UMF1) Family unknown 1 1
2.A.1.25 The Peptide-Acetyl-Coenzyme A Transporter (PAT) Family peptide, glycopeptide, acyl-CoA (symport)   3
2.A.1.30 The Putative Abietane Diterpenoid Transporter (ADT) Family diterpenoid (symport) 4  
2.A.1.34 The Sensor Kinase-MFS Fusion (SK-MFS) Family unknown 1  
2.A.1.35 The Fosmidomycin Resistance (Fsr) Family drug (antiport) 1  
2.A.1.36 The Acriflavin-sensitivity (YnfM) Family drug (symport) 2 1
2.A.1.40 The Purine Transporter, AzgA (AzgA) Family purine (symport) 2  
2.A.1.49 The Endosomal Spinster (Spinster) Family unknown   1
2.A.1.54 The Unknown (Archaeal/Bacterial) Major Facilitator-9 (UMF9) Family unknown 1  
2.A.1.60 The Rhizopine-related MocC (MocC) Family rhizopine 7 1
2.A.1.67 The Unidentified Major Facilitator-16 (UMF16) Family unknown 5  
2.A.17 The Proton-dependent Oligopeptide Transporter (POT) Family peptide, histidine, nitrate (symport; occasionally antiport) 1 2
  1. Representation of transporters belonging to known families within the Major Facilitator Superfamily (MFS) listed according to TC number with their substrate ranges and modes of active transport indicated.