Using phage display selected antibodies to dissect microbiomes for complete de novo genome sequencing of low abundance microbes

Table 2 HCDR3 sequences enriched from selection against a mock community

Rank	Unique HCDR3 sequence	Number of reads*	Frequency of reads	L. acidophilusBinder
1	CSTDDYGGNW	212506	17.7%	α-La2
2	CARAGRGTSYYGMDVW	142822	11.9%
3	CARVGDGYNYAFDIW	34320	2.9%
4	CAVAGTGYAFDIW	17429	1.4%
5	CARAGGGTSYYGMDVW	11394	0.9%
6	CAKLRGGPTKGDWYFDVW	9688	0.8%
7	CATGDAFDMW	9287	0.8%	α-La3
8	CARGHYGMDVW	7675	0.6%
9	CARDEGNAFDIW	7303	0.6%
10	CARGSLGAFDIW	5761	0.5%	α-La4
11	CAKLRGPTLPRYSFDYW	5601	0.5%
12	CARDPLGKLGPEEYYYGMDVW	4598	0.4%
13	CARDSMWVVAAKRKLHNCFDPW	4939	0.4%
14	CARDRGYGVDYW	3331	0.3%
15	CARDLGAGMDVW	3256	0.3%
16	CARQQLAAFDIW	3037	0.3%
17	CARDKGHEAFDIW	2589	0.2%
18	CARDGGDAFDIW	2029	0.2%
19	CARDYGEAFDIW	1585	0.1%
20	CARIGGGKRRSHFDYW	1438	0.1%

ISSN: 1471-2180