RMS | Mean ± SD frequency/1.00 bp | O/E ratiob | |||||
---|---|---|---|---|---|---|---|
Endonuclease/ Methylase | Cognate recognition sitea | MLS (N = 73) | WGS (N = 6) | ||||
 |  | Observed | Expected | Observed | Expected | MLS (N = 73) | WGS (N = 6) |
Hpy 166III | CCTC | 2.7 ± 0.41 | 5.49 ± 0.07 | 2.93 ± 0.02 | 4.50 ± 0.03 | 0.50 c | 0.65 |
Hpy178VI | GGATG | 1.48 ± 0.23 | 1.59 ± 0.03 | 0.81 ± 0.00 | 1.37 ± 0.01 | 0.93 | 0.59 |
Hpy17VII | GGCC | 1.24 ± 0.31 | 1.96 ± 0.05 | 0.98 ± 0.02 | 1.43 ± 0.02 | 0.63 | 0.68 |
Hpy188I | TCBGA | 1.02 ± 0.21 | 3.70 ± 0.03 | 0.81 ± 0.02 | 3.53 ± 0.01 | 0.28 | 0.23 |
Hpy188III | TCBBGA | 1.11 ± 0.22 | 3.70 ± 0.04 | 1.19 ± 0.02 | 3.53 ± 0.01 | 0.30 | 0.34 |
Hpy8I | GTNNAC | 0.40 ± 0.35 | 3.70 ± 0.03 | 0.22 ± 0.01 | 3.53 ± 0.01 | 0.11 | 0.06 |
Hpy8II | GTSAC | 0.00 ± 0.00 | 1.56 ± 0.02 | 0.05 ± 0.00 | 1.37 ± 0.01 | 0.00 | 0.04 |
Hpy8III | GWGCWC | 0.07 ± 0.12 | 0.66 ± 0.01 | 0.19 ± 0.01 | 0.19 ± 0.00 | 0.10 | 0.36 |
Hpy99I | CGWCG | 0.28 ± 0.06 | 1.13 ± 0.02 | 0.15 ± 0.01 | 0.88 ± 0.01 | 0.25 | 0.17 |
Hpy99III | GCGC | 4.62 ± 0.64 | 1.96 ± 0.05 | 3.73 ± 0.11 | 1.43 ± 0.02 | 2.36 | 2.60 |
Hpy99IV | CCNNGG | 1.62 ± 0.26 | 1.96 ± 0.05 | 0.70 ± 0.01 | 1.43 ± 0.03 | 0.83 | 0.49 |
Hpy99VIP | GATC | 5.48 ± 0.44 | 3.70 ± 0.03 | 3.19 ± 0.04 | 3.53 ± 0.01 | 1.48 | 0.90 |
Hpy99XIIP | GTAC | 0.37 ± 0.20 | 3.70 ± 0.04 | 0.07 ± 0.00 | 3.53 ± 0.01 | 0.10 | 0.02 |
HpyAV | CCTTC(6/5) | 0.58 ± 0.12 | 1.58 ± 0.02 | 0.80 ± 0.02 | 1.37 ± 0.01 | 0.37 | 0.58 |
HpyC1I | CCATC(4/5) | 1.94 ± 0.26 | 1.94 ± 0.26 | 1.60 ± 0.02 | 1.39 ± 0.01 | 1.22 | 1.01 |
HpyCH4II | CTNAG | 0.60 ± 0.28 | 3.70 ± 0.03 | 1.84 ± 0.04 | 3.53 ± 0.01 | 0.16 | 0.52 |
HpyCH4III | ACNGT | 0.89 ± 0.22 | 3.70 ± 0.04 | 0.34 ± 0.00 | 3.53 ± 0.01 | 0.24 | 0.10 |
HpyCH4IV | ACGT | 0.39 ± 0.22 | 3.70 ± 0.04 | 0.18 ± 0.01 | 3.53 ± 0.01 | 0.11 | 0.05 |
HpyCH4V | TGCA | 3.85 ± 0.75 | 3.70 ± 0.03 | 3.45 ± 0.03 | 3.53 ± 0.03 | 1.04 | 0.98 |
HpyCI | GATATC | 0.00 ± 0.03 | 0.31 ± 0.01 | 0.02 ± 0.00 | 0.33 ± 0.00 | 0.01 | 0.07 |
HpyF10VI | GCNNNNNNNGC | 2.70 ± 0.35 | 1.96 ± 0.04 | 2.97 ± 0.09 | 1.43 ± 0.02 | 1.38 | 2.07 |
HpyF14I | CGCG | 2.26 ± 0.46 | 1.96 ± 0.05 | 1.55 ± 0.05 | 1.43 ± 0.02 | 1.15 | 1.08 |
HpyF2I | CTRYG | 1.16 ± 0.17 | 0.92 ± 0.01 | 0.37 ± 0.01 | 0.88 ± 0.00 | 1.26 | 0.42 |
HpyF36IV | GDGCHC | 0.20 ± 0.21 | 1.22 ± 0.03 | 0.31 ± 0.01 | 0.93 ± 0.01 | 0.16 | 0.33 |
Hpy44II | GGNNCC | 1.21 ± 0.38 | 1.96 ± 0.05 | 0.44 ± 0.00 | 1.43 ± 0.02 | 0.62 | 0.31 |
HpyII | GAAGA | 2.29 ± 0.23 | 2.14 ± 0.03 | 2.87 ± 0.02 | 2.16 ± 0.00 | 1.07 | 1.33 |
HpyIP | CATG | 4.63 ± 0.25 | 3.70 ± 0.03 | 4.43 ± 0.04 | 3.53 ± 0.01 | 1.25 | 1.25 |
HpyIV | GANTC | 1.70 ± 0.25 | 3.70 ± 0.04 | 1.66 ± 0.02 | 3.53 ± 0.01 | 0.46 | 0.47 |
HpyNI | CCNGG | 2.04 ± 0.30 | 1.96 ± 0.05 | 0.87 ± 0.02 | 1.43 ± 0.02 | 1.04 | 0.61 |
HpyPORF1389P | GAATTC | 0.01 ± 0.05 | 0.31 ± 0.01 | 0.11 ± 0.00 | 0.33 ± 0.00 | 0.03 | 0.32 |
HpyV | TCGA | 0.95 ± 0.25 | 3.70 ± 0.03 | 0.18 ± 0.00 | 3.53 ± 0.01 | 0.26 | 0.05 |
HpyVIII | CCGG | 1.92 ± 0.30 | 1.96 ± 0.04 | 1.06 ± 0.02 | 1.43 ± 0.02 | 0.98 | 0.74 |