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Table 3 IL-1β secretion from F. tularensis-infected BMDM cells

From: The Francisella tularensis LVS ΔpdpCmutant exhibits a unique phenotype during intracellular infection

Strain IL-1β secretion (pg/ml)a
  5 h 24 h
- BDL*** BDL***
LVS 76.3 ± 10.9 497.1 ± 79.0
ΔiglC 39.6b BDL***
ΔpdpC 64.5 ± 27.2 112.1 ± 41.0*
ΔpdpC/pdpC 163.2 ± 50.2 506.9 ± 94.3
  1. aF. tularensis-infected, or uninfected (-) BMDM cells were incubated for 5 or 24 h. The average IL-1β secretion in pg/ml with standard errors of triplicate biological samples from one representative experiment, out of three, is shown. A Student’s t-test was used to determine if the IL-1β secretion was significantly different between LVS infected and mutant infected cells (*: P < 0.05, **: P < 0.01, ***: P < 0.001). BDL means that the concentration was below the detection limit of the assay (< 31.25 pg/ml).
  2. b Only one of the triplicates was above BDL.