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Table 2 IC 50 values (μM) of the naphthoquinones on the proliferation of T. cruzi epimastigotes

From: Trypanosoma cruzi mitochondrial swelling and membrane potential collapse as primary evidence of the mode of action of naphthoquinone analogues

Cpd

1 day

2 days

3 days

4 days

NQ1

0.30 ± 0.08a

0.24 ± 0.03

0.26 ± 0.04

0.26 ± 0.05

NQ8

0.76 ± 0.12

0.35 ± 0.09

0.24 ± 0.10

0.36 ± 0.07

NQ9

2.62 ± 0.38

1.05 ± 0.19

1.08 ± 0.17

1.27 ± 0.21

NQ12

0.55 ± 0.01

0.48 ± 0.06

0.45 ± 0.05

0.44 ± 0.11

  1. aMean ± standard deviation of at least three independent experiments.
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BMC Microbiology

ISSN: 1471-2180

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