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Table 3 Prediction of B-cell epitopes of DENV prM protein

From: Identification of a novel infection-enhancing epitope on dengue prM using a dengue cross-reacting monoclonal antibody

Predicted criteria

B epitope regions

Hopp & Wood hydrophilicity

5–10, 12–26, 42–47, 56–66, 83–94, 102–112, 115–122

Granthan polarity

5–9, 15–20, 58–63, 83–91, 116–118

Jameson & Wolf antigenicity

3–12, 14 – 24, 26–33, 40–53, 56–73, 81–94, 111–118, 130–133

Bhaskara & Ponnuswamy flexibility

5–9, 15 – 20, 55–66, 85–91, 103–106, 108–118

Emini accessibility

3–9, 15 – 21, 24–29, 47–50, 56–62, 82–92, 104–110, 119–124

Deleage & Roux alpha-helix regions

5–12, 16–19, 23–34, 44–58, 62–83, 94–104, 127–135, 142–150

Deleage & Roux beta-turn regions

5–9, 16 – 26, 28–32, 55–63, 84–89, 114–118

  1. Notes: The possible predominant B epitope region showing conformity with the result of phage-displayed peptide library is shown in bold.