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Table 2 Alignment of amino acid residues 14 to 18 of the prM proteins of flaviviruses with binding motif VS/GKTE

From: Identification of a novel infection-enhancing epitope on dengue prM using a dengue cross-reacting monoclonal antibody

Virusa

Amino acid sequence

Binding motif

VS/GKTE

DENV1

IVSKQERGKSLL

DENV2

IVSRQEKGKSLL

DENV3

IVGKNERGKSLL

DENV4

IVAKHERGRPLL

WNV

TVNATDVTDVIT

JEV

TINNTDIADVIV

YFV

NVTSEDLGKTFS

TBEV

AEGKDAATQVRV

  1. Notes: aThe protein sequences of DENV1, DENV2, DENV3, DENV4, WNV, JEV, YFV and TBEV were retrieved from GenBank with accession numbers EU848545, AF038403, M93130, AY947539, DQ211652, AF315119, X03700 and AY182009 respectively. The amino acids identical between the binding motif and prM protein are shown in bold.