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Table 2 Genotypes identified in PCR positive swabs and whole blood samples

From: Comparison of CDC and sequence-based molecular typing of syphilis treponemes: tpr and arp loci are variable in multiple samples from the same patient

Genes   Type of sample Statistical significance
  Locus nucleotide sequences Swabs (n = 93) WB samples (n = 34)  
TP0136 Identical to strain SS14 96.1% (74/77) 100.0% (12/12)  
  Unique sequences 3.9% (3/77) 0.0% (0/12)  
TP0548 Identical to strain SS14 74.4% (58/78) 68.8% (11/16)  
  Unique sequences 25.6% (20/78) 31.3% (5/16)  
23S rDNA wt 60.4% (55/91) 51.6% (16/31)  
  A2058G 28.6% (26/91) 25.8% (8/31)  
  A2059G 11.0% (10/91) 22.6% (7/31)  
  Number of repetitions in the arp locus   
   Swabs WB samples  
arp 14 82.4% (56/68) 55.6% (5/9) p = 0.03
  15 11.8% (8/68) 11.1% (1/9)  
  8-12 5.9% (4/68) 33.3% (3/9) p = 0.003
tpr E, G, J tpr E, G, J pattern after Mse I digest    
   Swabs WB samples  
  d 91.2% (62/68) 30.8% (4/13) p < 0.001
  e 1.5% (1/68) 46.2% (6/13) p < 0.001
  b, p, k, j 7.4% (5/68) 23.1% (3/13)  
  1. Samples isolated in the work of Flasarová et al. [17] augmented by samples collected in 2011 in the Czech Republic were analyzed. Results show both paired and unpaired samples.
  2. wt, wildtype.