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Table 1 Molecular typing of treponemal DNA isolated from a set of 16 patients with two or more samples positive for treponemal DNA

From: Comparison of CDC and sequence-based molecular typing of syphilis treponemes: tpr and arp loci are variable in multiple samples from the same patient

Patient no.

Syphilis stage

Sample

Material

Genotypes based on TP0136, TP0548, 23S rDNA

CDC subtype

Enhanced CDC subtype*

1

Primary

43K StI

Swab

SSS

14d

14d/f

  

44K StII

Swab

SSS

14d

14d/f

2

Primary

36K St

Swab

SU2R8

14d

14d/g

  

37K

Whole blood

SU2R8

12d

12d/g

3

Primary

93K

Swab

SXS

14k

14k/X

  

94K

Whole blood

XSX

14e

14e/f

4

Primary

891

Swab

SSS

14d

14d/f

  

892

Swab

SSS

14p

14p/f

5

Primary

91K

Swab

SSR8

14d

14d/f

  

92K

Whole blood

SXX

12e

12e/X

6

Primary

C-150

Swab

U1SS

8b

8b/f

  

D-151

Swab

U1SS

8d

8d/f

7

Primary

8032

Swab

SSR9

15d

15d/f

  

8284

Swab

SSR9

15d

15d/f

8

Primary

19512

Swab

SU2R8

14d

14d/g

  

19527

Swab

SU2R8

14b

14b/g

9

Primary

15K St

Swab

SSS

14d

14d/f

  

16K

Whole blood

XSS

XXe

XXe/f

10

Primary

RL104BZ

Swab

SU2R8

14d

14d/g

  

RL104AZ

Whole blood

XU2R8

14X

14X/g

11

Primary

63K

Swab

SSR9

15d

15d/f

  

62K

Whole blood

XSR9

15d

15d/f

12

Primary

4K

Swab

SSS

14d

14d/f

  

5K

Swab

SSS

14d

14d/f

13

Primary

34K St

Swab

SSS

14d

14d/f

  

35K

Whole blood

XXS

XXe

XXe/X

14

Primary

RL116A

Swab

SU2R8

14e

14e/g

  

RL116B

Whole blood

SXR8

14j

14j/X

15

Secondary

15577

Swab

SXS

14d

14d/X

  

15578

Swab

SSS

14d

14d/f

16

Secondary

G-269

Swab

SU1S

14p

14p/f

  

H-270

Swab

SU1S

14d

14d/f

17

Secondary

51K

Swab

SSS

14d

14d/f

  

52K

Swab

SSS

14d

14d/f

18

Secondary

73K

Swab

SU2R8

14d

14d/g

  

74K

Whole blood

XXR8

XXe

XXe/X

  1. X, the exact genotype was not determined.
  2. *subtype identification based on CDC typing enhanced by sequence analysis of TP0548 between position 131–215 [14].