Figure 2
From: Characterization of the PAS domain in the sensor-kinase BvgS: mechanical role in signal transmission
Structural model for PAS Bvg . The modeled sequence encompasses residues 564–697 of BvgS, thus immediately following the predicted transmembrane segment of BvgS. The segment after the PAS core has not been modeled, because the corresponding segment is absent from the PASHm X-ray structure. In BvgS this segment is predicted to form an α helix linking the PAS and kinase domains. In yellow are shown residues whose substitutions were previously reported to abolish the responsiveness of BvgS to negative modulation (see discussion).