Figure 1

Sequence of PAS _Bvg and flanking regions and of the recombinant proteins produced in this work. The predicted secondary structures are shown above the sequence, with H and S representing α helices and β strands, respectively. The secondary structure elements characteristic of PAS domains have been numbered from A to I. The arrows indicate the borders of the recombinant proteins (see text). The residues modified by site-directed mutagenesis are marked by asterisks and numbered. The C-terminal part of the sequence comprises the dimerization helix of the kinase (DHp) including the phosphorylated His (highlighted). The numbering starts at the initiation Met of BvgS.