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Table 2 Fold-change in fluorescence of H33342 at steady state level accumulation in the presence of EIs in efflux pump mutants and parental strains

From: A Method for generating marker-less gene deletions in multidrug-resistant Acinetobacter baumannii

Bacterial strain +CCCPa +PAβNb
DB 1.51 ± 0.04 1.29 ± 0.11
DBΔadeFGH 1.27 ± 0.12 1.28 ± 0.03
DBΔadeIJK 1.16 ± 0.06 1.24 ± 0.13
DBΔadeFGH ΔadeIJK 1.19 ± 0.03 1.36 ± 0.07
R2 1.31 ± 0.12 1.27 ± 0.04
R2ΔadeFGH 1.46 ± 0.04 1.29 ± 0.03
R2ΔadeIJK 1.09 ± 0.01 1.29 ± 0.05
R2ΔadeFGH ΔadeIJK 1.10 ± 0.01 1.20 ± 0.10
  1. Three separate experiments showed consistent results and representative examples are shown. The standard deviation represents variation between three biological replicates. All values shown are significant differences (P ≤ 0.05) in accumulation with addition of an EI relative to absence of EI.
  2. a fold-change compared to corresponding bacterial sample in the absence of CCCP.
  3. b fold-change compared to corresponding bacterial sample in the absence of PAβN.