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Table 3 Distribution of virulence genes (%) in ESBL-producing E. coli isolates

From: Molecular epidemiology of extended-spectrum beta-lactamase-producing Escherichia coli in Tunisia and characterization of their virulence factors and plasmid addiction systems

Virulence factors Total CTX-M producers Non CTX-M producers CTX-M-15 producers CTX-M-15 B2 producers B2 non-ST131 B2 ST131 CTX-M-15 B2 ST131producers
  N = 163 (%) N = 118 N = 45 N = 101 N = 52 N = 37 N = 24 N = 23
Total 910 730 180 671 463 332 193 186
Mean 5.58 6.18 4.0 6.64 8.90 8.97 8.04 8.08
Adhesin 3 (1.8) 2 (1.6) 1 (2.2) 2 (1.9) - 1 (2.7) - -
papG I
papG II 21 (12.8) 19 (16.1) * 2 (4.4) 19 (18.8)‡ 15 (28.8) † 10 (27.2) 5 (20.8) 5 (21.7)
papG III 36 (22.0) 30 (25.4) 6 (13.3) 30 (29.7) ‡ 25 (48.0) † 24 (64.8) γ 4 (16.6) 4 (17.3)
papC 35 (21.4) 29 (24.5) 6 (13.3) 29 (28.7) ‡ 25 (48.0) † 25 (67.5) γ 3 (12.5) 3 (13)
fimH 138 (84.7) 100 (84.7) 38 (84.4) 85 (84.2) 51 (98.1) † 36 (97.3) 24 (100) 23 (100)
afa/draBC 8 (4.9) 4 (3.3) 4 (8.8) 4 (3.9) 2 (3.8) 3 (8.1) 1 (4.1) 1 (4.3)
sfa/foc 26 (15.9) 20 (16.9) 6 (13.3) 20 (19.8) ‡ 18 (34.6) † 22 (59.4) γ - -
iha 49 (30.0) 45 (38.1) * 4 (8.8) 43 (42.5) ‡ 36 (69.2) † 14 (37.8) γ 24 (100) 23 (100)
hra 38 (23.3) 29 (24.5) 9 (20.0) 28 (27.7) 19 (36.5) † 24 (64.8) γ - -
Iron uptake 104 (63.8) 78 (66.1) 26 (57.7) 68 (67.3) 49 (94.2) † 33 (89.1) 24 (100) 23 (100)
fyuA
iutA 82 (50.3) 65 (55.0) * 17 (37.7) 60 (59.4) ‡ 37 (71.2) † 16 (43.2) γ 24 (100) 23 (100)
Toxin 27 (16.5) 24 (20.3) * 3 (6.6) 23 (22.8) ‡ 22 (42.3) † 24 (64.9) γ 2 (8.3) 2 (8.6)
hylA
cnfI 19 (11.6) 17 (14.4) 2 (4.4) 17 (16.8) ‡ 14 (26.9) † 15 (40.5) γ - -
sat 38 (23.3) 37 (31.3) * 1 (2.2) 35 (34.6) ‡ 30 (57.6) † 8 (21.6) γ 24 (100) 23 (100)
Cell protection 119 (73.0) 94 (79.6) * 25 (55.5) 84 (83.2) ‡ 40 (76.9) 28 (75.5) 18 (75) 18 (78.2)
traT
kpsM II 69 (42.3) 64 (54.2) * 5 (11.1) 59 (58.4) ‡ 45 (86.5) † 27 (72.9) γ 23 (95.8) 22 (95.6)
Other pheR 98 (60.1) 73 (61.8) 25 (55.5) 65 (64.3) 35 (67.3) 22 (59.4) 17 (70.8) 16 (69.5)
  1. *: p < 0.05 for CTX-M producers vs. non CTX-M producers.
  2. ‡: p < 0.05 for CTX-M-15 producers vs. non CTX-M producers.
  3. †: p < 0.05 for CTX-M-15 B2 producers vs. other phylogroup isolates with CTX-M-15.
  4. γ: p < 0.05 for B2 non-ST131 isolates vs. B2 ST131 isolates.