Skip to main content

Table 1 Extracellular DNA induces antibiotic resistance in S. Typhimurium

From: Extracellular DNA-induced antimicrobial peptide resistance in Salmonella enterica serovar Typhimurium

Strain Minimal inhibitory concentration (MIC)
Polymyxin B Colistin Gentamicin Ciprofloxacin
  - + DNAa - + DNAa - + DNAa - + DNAa
14028 1 16 1 16 0.125 0.5 0.125 >0.5
phoPQ 1 0.5 1 1 0.125 0.25 0.125 >0.5
ΔpmrAB 0.5 0.5 0.5 0.5 0.125 0.5 0.125 >0.5
  1. a The minimal inhibitory concentration (MIC) values were determined in NM2 medium containing 1 mM Mg2+ (pH 7.4) with or without the addition of 0.5% fish sperm DNA-sodium salt (5 mg/ml).